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Author

Dante Jimenez

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Open access Sep 2026

Female-Biased IL-17–STAT3 Signaling Marks Dementia-Associated Microglial Inflammation in Alzheimer’s Disease

INTRODUCTION Alzheimer’s disease (AD) disproportionately affects women, but the underlying mechanisms are not fully understood. We compare sex-specific molecular changes across AD with and without dementia at single-cell resolution. METHODS We performed sex-stratified single-nucleus transcriptomic analysis of human AD...

Nourhan Abdelfattah, Reece Kang, Dante Jimenez et al. · 0 citations

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