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Author

Daphne E. Cruz-Villarreal

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Review Open access Sep 2026

Role of Protein Kinase C in Insulin Resistance and Metabolic Syndrome

One mechanism contributing to insulin resistance is the serine/threonine phosphorylation of critical proteins involved in insulin signaling, particularly the insulin receptor, its downstream substrates, and the activation of protein tyrosine phosphatases. These modifications are associated with decreased insulin signal...

Daphne E. Cruz-Villarreal, Karla D. Hernández-González, J. Olivares-Reyes · 0 citations

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