Author

Darex J. Vera-Rodriguez

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Open access Aug 2026

Incidental conformational switching in an allosteric enzyme

It is proposed that the observed T-to-R switching in CM is “incidental”, a byproduct of an evolved energy landscape that allows access to the substrate-bound pose but does not mechanistically determine affinity.

P. J. Sapienza, Darex J. Vera-Rodriguez, T. Mileur et al. · bioRxiv · 0 citations