Author

Darrell H. G. Crawford

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Review Open access Sep 2026

The convergent roles of metabolic dysfunction, alcohol, and iron in steatotic liver disease: a review

Abstract Steatotic liver disease (SLD) encompasses a broad spectrum of disorders influenced by metabolic dysfunction, alcohol use, and other cofactors. The updated classification of metabolic dysfunction-associated steatotic liver disease (MASLD) and alcohol-associated liver disease (ALD), along with the recognition of...

Afolabi Akanbi, Kim R. Bridle, Darrell H. G. Crawford · Bioscience Reports · 0 citations

Open access Aug 2026

Mesenchymal stem cell-derived liver-on-a-chip reconstitutes human liver structure and function.

An in vitro model of human liver with functional integrity would advance liver research and enable personalized therapeutics. A microfluidic liver-on-a-chip can generate a functional hepatobiliary network using human liver cells and recapitulate blood circulation and bile excretion. However, many current microfluidic l...

Anastasia Brooks, Haotian Yang, D. Barkauskas et al. · Cell Reports Methods · 0 citations