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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Darwin Daniel Campos González

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Review Open access Oct 2026

The NMDA receptor in opioid-induced hyperalgesia: From neuroplasticity to perioperative prevention- Narrative review

Importance. Opioid-induced hyperalgesia (OIH) is a paradoxical increase in nociceptive sensitivity attributable to opioid exposure. In the perioperative period, recognition is difficult because pain from surgical injury, inadequate analgesia, pharmacological tolerance, and acute withdrawal produce overlapping phenotype...

Gloria Anabel Ortiz Cruz, Oscar Leonardo Castillo Cueva, Darlyn Dayana Arciniega Guerrero et al. · 0 citations

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