David A. Rincón

Hydration Ensembles in Proton-Linked Amino-Acid Recognition by Cucurbit[7]uril

The hydrophobic effect is often considered a major driving force for molecular recognition in water, whether through classical desolvation of nonpolar surfaces or through the release of confined high-energy water from host cavities. However, the interplay between protonation, ion–dipole interactions, and hydration re...