David C. Henshall

A non-destructive workflow for simultaneous reconstruction of nuclear and dendritic architecture in intact brain tissue.

Neurons display elaborate dendritic and axonal structures which serve as input and output sites for the transmission of information across the nervous system. Changes to the structure and complexity of both are commonly reported in genetic and acquired brain diseases with neuropathology studies also reporting changes t...

P2X7 receptor antagonism potentiates seizure-suppressive effects of anti-seizure medications in human resected epileptic brain tissue

WONOEP appraisal: Biomarkers and treatment strategies beyond the synapse.

The review emphasizes the need for further interdisciplinary collaboration to accelerate the translation of these findings into clinical practice, ultimately improving outcomes and quality of life for people with epilepsy.