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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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David Fenyö

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Open access Jul 2026

Pan-cancer proteogenomic interrogation of the ubiquitin-proteasome system.

Somatic mutations rewire the ubiquitin-proteasome system (UPS) to support tumor growth, but the proteome-wide consequences of cancer-driver alterations on UPS composition remain incompletely understood. Using harmonized proteogenomic data from up to 11 CPTAC cohorts, we performed an integrated pan-cancer analysis of UP...

Tania J. González-Robles, Maha Khan, Paul Sastourné et al. · 0 citations

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