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Author

David Freudenstein

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Open access Aug 2026

Diroximel fumarate confers neuroprotection via reduced Th1 responses and induction of the anti-oxidative Nrf2 pathway in experimental neuroinflammation

NDF treatment markedly ameliorated clinical EAE severity, reduced spinal cord infiltration of T cells—particularly Th1 cells—and promoted myelin and axonal preservation, supporting its role as beneficial modulator in neuroinflammation.

David Freudenstein, Anna Schneeweiss, Adriana Krenz et al. · 1 citation

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