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Review Open access Sep 2026

State of clinical AI in 2026

Abstract Clinical artificial intelligence (AI) has advanced rapidly, with frontier large language models now matching or exceeding physician performance on simulated diagnostic reasoning and clinical decision-support tasks. Yet adoption has outpaced the evidence base: fewer than 5% of cleared U.S. Food and Drug Adminis...

J. Worth, Anastasia Perez, David Wu et al. · 1 citation
Preprint Sep 2026

A Living Benchmark for Information Retrieval from Electronic Health Records

A scalable framework that automatically generates question--answer pairs from longitudinal EHR notes that supports evaluations that static benchmarks cannot, including the generation of multiple answers that reflect variation in clinician reasoning for robust performance assessment and continuously refreshing benchmark...

J. Cahoon, C. Stanwyck, Sulaiman Somani et al. · 1 citation
#artificial intelligence Preprint Sep 2026

A Living Benchmark for Information Retrieval from Electronic Health Records

Large language model (LLM)-based clinical assistants are increasingly being integrated into electronic health record (EHR) systems, transforming how clinicians retrieve and synthesize information from patient records. Their safety and utility depend on rigorous evaluation, yet existing benchmarks are manually curated,...

J. Cahoon, C. Stanwyck, Sulaiman Somani et al. · 0 citations
#artificial intelligence Review Sep 2026

A primer on evaluation methods for large language models in healthcare

This article aims to provide a pragmatic basis for designing and executing rigorous evaluations of healthcare LLMs by describing underlying concepts and potential pitfalls, while emphasizing the importance of aligning evaluation methods with the research question.

S. E. McKinney, P. Vu, S. Justice et al. · 0 citations

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