Spatial Proteomics Uncovers Immune Cell Neighborhoods and Tumor-Immune Interfaces in Pancreatic Ductal Adenocarcinoma.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies with dismal prognosis and limited treatment options. The complex interplay between tumor cells and their microenvironment contributes significantly to treatment resistance, yet technological challenges have hindered comprehensive spatia...