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Author

David R. Lynch

2 papers indexed here

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Open access Oct 2026

A deep learning framework for automated cervical spinal cord vertebral labeling and morphometric extraction from brain MRI with large-scale multicenter validation

This study aimed to develop and validate a fully automated pipeline for vertebral level identification (C1–C3) of the upper cervical spinal cord (SC) in T1-weighted brain MRI with a quality control module to assess the generated masks. MRI data from 998 controls and 879 patients with hereditary ataxias (32 sites; age...

G. M. Jarola, D. H. Shiraishi, I. Adanyeguh et al. · 0 citations
Open access Aug 2026

Impaired Glur2 Palmitoylation in Cerebellar Purkinje Cells of a Friedreich Ataxia Mouse Model

Friedreich’s ataxia (FRDA) is a neurodegenerative disorder caused by frataxin deficiency, characterized by progressive cerebellar dysfunction and neuronal loss. Although synaptic abnormalities are an early feature of FRDA, the molecular mechanisms linking frataxin deficiency to synaptic dysfunction remain incompletely...

Elizabeth Mercado-Ayón, Jennifer Coulman, J. Lee et al. · 0 citations

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