Review
Open access
Sep 2026
Spatial Treg niches and the therapeutic reprogramming of tumour tolerance in cancer
Regulatory T cells (Tregs) maintain immune homeostasis, but in cancer the same FOXP3-dependent programme can be co-opted to protect malignant tissue from immune elimination. This review critically synthesizes spatially resolved, single-cell and mechanistic evidence to determine when tumour-associated Tregs constitute a...
Jhommara Bautista, Miranda Di Capua Delgado, Juliana Viteri-Recalde et al.
· Frontiers in Cell and Develo... · 0 citations