Preprint
Oct 2026
Composite Variable Strategies for Continuous Endpoints
Composite endpoints are common in clinical trials for binary, time-to-event or recurrent outcomes. Recently, there has been interest in estimands for continuous endpoints that employ a composite variable strategy for handling intercurrent events, whereby a value on the continuous scale is defined as the outcome. In thi...
J. Bell, O. Keene, C. Pipper et al.
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