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Author

De-Gao Wang

2 papers indexed here

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Open access Oct 2026

Insights into pyrazinone biosynthesis from biochemical and cryo-EM studies of the hybrid NRPS-PKS enzyme CorA

Hybrid nonribosomal peptide synthetase-polyketide synthase (NRPS-PKS) systems integrate peptide and polyketide biosynthetic logic to assemble complex natural products. CorA, a prototypical NRPS-PKS hybrid from the myxobacterium Corallococcus exiguus SDU70, is responsible for producing 5-alkylated pyrazinones, a family...

Qing-Yu Yang, Qian Wang, Xiao-Ju Li et al. · 0 citations
Review Open access Oct 2026

Integrated genomics and metabolomics survey of steroids from myxobacteria

An integrated genomics–metabolomics pipeline is established that not only expands the structural repertoire of myxobacterial steroids but also provides a blueprint for future discovery of cryptic sterol metabolites and their hidden biological functions.

Bing-Jie Fan, Luo Niu, Teng Liu et al. · 0 citations

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