FTY720 attenuates LPS-induced acute lung injury through PP2A- tristetraprolin–dependent anti-inflammatory signaling
Acute lung injury (ALI) is characterized excessive inflammatory signaling and uncontrolled cytokine production. Tristetraprolin (TTP) is a key post-transcriptional regulator of inflammatory cytokines that negatively regulates inflammatory pathways. PP2A emerges as an important player to activate TTP. However, wheth...