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Open access Sep 2026

Engineered Human Ferritin Nanocage Enhances Intracellular Vancomycin Delivery and Activity Against Gram-Positive Bacteria in Macrophages

Purpose The limited cellular penetration of vancomycin (Van) restricts its intracellular availability and represents a major challenge for treating infections caused by intracellular Gram-positive bacteria. We investigated whether the engineered ferritin nanocage HFn-D93G could improve intracellular Van delivery while...

Bin-Wang Cao, Man-Xian Wang, Tao Li et al. · 0 citations

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