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Dean A. Lee

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Oct 2026

B-216 Validation and Optimization of AAV9 Total Antibody Testing in Gene Therapy

Adeno-associated virus serotype 9 (AAV9) is widely used as a gene therapy vector. Pre-existing anti-AAV9 antibodies can reduce transduction efficiency and pose safety risks, making accurate antibody detection essential for patient selection and immune monitoring. However, despite its importance, current laborator...

Jing Wang, K. Everhart, Dean A. Lee et al. · 0 citations

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