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Open access
Aug 2026
Clinical Functional Assignment of TPMT and NUDT15 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel
The work presented here includes the first designation of decreased function alleles for both TPMT and NUDT15, reflecting new clinical data that demonstrate partial loss of enzymatic activity and reduced dose tolerance.
Bailey M. Tibben, Maud Maillard, Victoria M. Pratt et al.
· Clinical pharmacology and th... · 0 citations