Circadian disruption and metabolic dysfunction are linked to chronic disease, but whether circadian syndrome, which combines metabolic, sleep, and mood traits, relates to overall and site-specific cancer risk remains unclear. We prospectively studied 367,832 cancer-free participants in the UK Biobank, of whom 82,547 (2...
Jie Wang, Feipeng Jiang, Rui-Cheng Wu et al.· Research· 0 citations
Benign urological and andrological diseases (BUADs) represent common yet complex clinical challenges, where the diversity and dynamic nature of their microenvironments substantially influence disease onset and progression. In recent years, the emergence of single-cell RNA sequencing (scRNA-seq) and spatially resolved t...
Yan-Dong Xie, Jun-Jiang Ye, Jie Wang et al.· Research· 0 citations
Midkine (MDK) is a heparin-binding growth factor that is minimally expressed in most adult tissues but markedly upregulated in a wide range of malignancies. Accumulating evidence positions MDK as a multifunctional signaling hub that orchestrates tumor progression through its pleiotropic effects on cancer cells and the...
D. Wusiman, Xue-Zeng Yang, Xiao‐Tong Yan et al.· Cancer Genetics· 0 citations
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