Open access
Sep 2026
Complete disruption of gD binding to HVEM alters virus replication and host receptor homeostasis
Herpes simplex virus 1 (HSV‑1) establishes infection through coordinated interactions of multiple viral glycoproteins with host cell receptors. Interactions between the viral glycoprotein D (gD) and the immunomodulatory cellular receptor HVEM (herpesvirus entry mediator) critically influence HSV‑1 latency and reactivat...
Deepak Arya, Kati Tormanen, Jay J. Oh et al.
· PLoS Pathogens · 0 citations