Review
Open access
Oct 2026
Organoids as advanced three-dimensional models for studying brain development, neurodegeneration, and translational therapeutics
Organoids are stem cell-derived three-dimensional (3D) multicellular constructs that recapitulate key cytoarchitectural, molecular, and functional properties of their tissue of origin. Two fundamentally distinct strategies govern their generation: unguided approaches, which exploit intrinsic self-organization to prod...
Vikram, Shiv Kumar, Deepak Nathiya et al.
· Molecular Brain · 0 citations