5-indole-appended 1,3,4-Oxadiazole/Oxadiazolinethione hybrids: Synthesis, crystal structure, antimicrobial and antibiofilm evaluation.
A series of eleven new 5-indole-appended 1,3,4-Oxadiazole/Oxadiazolinethione derivatives 5(a-k) was synthesized via nucleophilic substitution of 5-(1H-indol-2-yl)-1,3,4-oxadiazoline-2(3H)-thione (3) with sugar and non-sugar halides 4(a-k). The structures of the synthesized compounds were established by FT-IR, NMR, and...