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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

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Deivasigamani Gavaskar

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Open access Aug 2026

Structure-based Design and Computational Evaluation of Spiropyrrolidine Derivatives as Novel Acetylcholinesterase Inhibitors for Alzheimer’s Disease

Acetylcholinesterase (AChE; E.C. 3.1.1.7) is a key enzyme involved in cholinergic neurotransmission, catalyzing the hydrolysis of acetylcholine (ACh). Reduced ACh levels are associated with Alzheimer's disease (AD), making AChE inhibition an effective therapeutic strategy. Structurally, AChE possesses a deep active sit...

Paranthaman Shamala, Mohamed Noor Shaik, P. B. et al. · 0 citations

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