Microenvironment-Dependent Role of PLOD3 in Glioblastoma: Associations with Matrix Remodeling and Myeloid Immune Remodeling.
INTRODUCTION/OBJECTIVE Glioblastoma progression depends on reciprocal interactions between malignant cells, extracellular matrix remodeling, and myeloid immune suppression. However, whether PLOD3 drives glioblastoma through tumor cell-intrinsic or microenvironment- dependent mechanisms remains unclear. METHODS This r...