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Author

Denis Gris

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2 papers indexed here

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Review Open access Sep 2026

Engineering Polymeric Vectors for Nucleic Acid Delivery: Linking Molecular Architecture, Biological Function, and Computational Design

This review examines how molecular weight, polymer composition, cationic group chemistry and density, pKa, and polymer topology influence complexation efficiency with nucleic acid, polymer to nucleic acid ratio (N/P), polyplex stability, cellular uptake, endosomal escape, cytotoxicity, and transfection efficiency.

Joachim Emeka Arikibe, Anna Maria Mazzetta, Lisa Casagrande et al. · 0 citations
Jul 2026

Effects of the Antiretroviral Raltegravir on Amyloid-Beta1-42-Induced Neuroinflammation 2310253

There is growing evidence supporting the potential role of microbial infections in the aetiology of Alzheimer’s disease (AD). We aim to evaluate the effect of raltegravir, either alone as a single therapy or combined with elacridar, a P-gp/BCRP inhibitor, on AD-related pathways in vitro. Flow cytometry com...

Tamas Fulop, Hicham Berrougui, Ton Bunt et al. · 0 citations

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