Denisa Kirdajova

Canonical Wnt signaling regulates NG2 glia fate and plasticity in healthy and ischemic cortex

NG2 glia, also known as oligodendrocyte precursor cells, display unexpected plasticity in the adult brain after injury, yet the molecular cues guiding their fate remain unclear. The Wnt signaling pathway contributes to post-stroke responses, but its role in glial remodeling is not well defined. Here, we show that Wnt...