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Dennis G. Hall

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Oct 2026

Benzoxaborole-Inspired p K a-Guided Search for a Borine Alternative Uncovers a Borylurea Scaffold with Unique Properties and Reactivity

The advent of benzoxaborole drugs brought attention to hemiboronic heterocycles as an attractive chemotype, where they can be implicated in a number of biological contexts. However, the success of benzoxaboroles, a neutral-pKa scaffold, has yet to be replicated with other classes of boranol (B–OH)-containing heterocy...

Olivia M. Schneider, Jake J. Blackner, Joana Sugiarto et al. · 0 citations

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