Deok-Sang Hwang

Melittin Reprograms Tumor-Associated Macrophages Through CD18-Mediated Immunomodulation.

Tumor-associated macrophages (TAMs), particularly the M2-like subtype, contribute to an immunosuppressive tumor microenvironment and promote tumor progression. Melittin, a natural bioactive peptide derived from bee venom, has been reported to exert anticancer and immunomodulatory effects; however, the cellular targets...