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De-Pei Wu

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Aug 2026

Transmembrane Protein Disulfide Isomerase TMX3 Potentiates Platelet Aggregation and Arterial Thrombosis in Mice.

BACKGROUND Several members of the PDI (protein disulfide isomerase) family have been shown to regulate platelet function and thrombosis. TMX3 (thioredoxin-related transmembrane protein 3), the sole transmembrane member of the PDI family containing catalytically inactive thioredoxin-like domains, has been implicated in...

Feng-Wu Chen, Xiao-Feng Yan, Yu-Xin Zhang et al. · 0 citations
Open access Jul 2026

Rbm5 sustains leukemia stem cells through a Myc-driven transcriptional circuitry.

It is reported that an unappreciated RNA-binding protein, Rbm5, selectively promotes murine leukemogenesis, maintains LSC self-renewal in vivo, and is dispensable for normal hematopoiesis.

Mengli Zhang, Shaela Fields, Qiong Zhang et al. · 0 citations

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