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Author

Desheng Xiao

2 papers indexed here

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Review Open access Sep 2026

Immune checkpoints and immunoregulation in metabolic diseases and cancers: pathological mechanisms and therapeutic potential

The global prevalence of metabolic diseases, notably obesity, diabetes mellitus, and thyroid disorders, has risen dramatically in recent decades, posing a significant threat to public health. While conventional pharmacological interventions remain the cornerstone of management, they face considerable limitations, inclu...

Min-Min Xiang, Shuang Liu, De-Sheng Xiao et al. · 0 citations
Aug 2026

Adaptor AP4M1 promotes hepatocellular carcinoma progression by inhibiting ferroptosis through USP15-mediated deubiquitination and MINK1-dependent phosphorylation.

It is shown that AP4M1 is markedly upregulated in HCC, correlates with unfavorable prognosis, and is functionally involved in driving HCC progression, providing a critical theoretical basis for AP4M1-targeted therapeutic strategies in HCC.

Yuan-Hao Peng, K. Kang, Xuanxuan Li et al. · 0 citations

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