Open access
2026
Nanoparticle-based dual-triggered colon-targeted 5-fluorouracil tablets: A quality-by-design approach for improved colorectal cancer therapy
A pH- and microflora-activated colon-targeted tablet containing 5-FU-loaded, folic acid-conjugated chitosan (FA-CS) nanoparticles for site-specific CRC therapy was designed and optimized to achieve delayed colon-targeted release.
Yash Dipakkumar Dudhwala, Dhiren Prafulbhai Shah, Devesh Umesh Kapoor et al.
· Pharmaceutical Sciences Asia · 0 citations