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Author

Devin J. Hunt

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Open access Sep 2026

Safety and immunogenicity of a recombinant vesicular stomatitis virus-based Sudan virus vaccine in adults in the USA: a single-blind, first-in-human, dose-escalation phase 1 clinical trial.

BACKGROUND A vaccine is needed to prevent Sudan virus (SUDV) disease (SVD), a haemorrhagic fever. We report a first-in-human clinical trial evaluating the safety and immunogenicity of a recombinant vesicular stomatitis virus (rVSV) vaccine expressing the SUDV envelope glycoprotein (rVSVΔG-SEBOV-GP). METHODS In this s...

Dagna S. Laufer, Arianna Marini, V. Philiponis et al. · 1 citation

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