Microglial Mitophagy in Brain Aging: A Conceptual Framework Linking Mitochondrial Resilience, Lysosomal Function, and Inflammaging
Brain aging is characterized by heterogeneous microglial states and altered mitochondrial, metabolic, and lysosomal homeostasis. Mitophagy is central to mitochondrial quality control, but its contribution to age-associated microglial dysfunction remains incompletely understood. This review examines how microglial mitop...