Open access
Jul 2026
Microbiota-dependent IGF-1 limits alveolar macrophage inflammatory function 2257596
It is found that IGF1R deficiency in AECs largely recapitulates AM phenotypes overserved in germ-free mice, with increased phagocytic capacity and enhanced inflammatory cytokine production in response to microbial stimuli.
Sonia M. Kruszelnicki, Devon Colby, Kay Bajpai et al.
· Journal of Immunology · 0 citations