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Dhruv Nambiar

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Open access Sep 2026

3D Spatial Interactomics Maps the Dynamics of NF-κB Multiprotein Signalosomes in Single Cells

NFκB signaling drives inflammatory responses by rapidly assembling membrane-proximal multiprotein supercomplexes, yet how these assemblies are organized in space and time within the 3D interior of a single cell has remained uncharacterized. We addressed this by profiling endogenous NFκB protein-protein interactions wit...

Nicholas Zhang, Collin Leese-Thompson, H. Ozuna et al. · 0 citations

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