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Open access Oct 2026

Mycobacterium tuberculosis gene expression dynamics in host environments with single-cell resolution.

Visualizing when and where Mycobacterium tuberculosis (Mtb) genes are expressed in the host cell is crucial to understand tuberculosis heterogeneity. However, imaging approaches for studying spatiotemporal gene expression in Mtb remain limited. Here, we developed a dual-fluorophore Mtb reporter system that enables high...

Beren Aylan, Laure Botella, Pierre Santucci et al. · 0 citations
Open access Sep 2026

DFCP1-containing ER microdomains mediate lysosomal membrane repair

Lysosomal membrane integrity is essential for preserving cellular homeostasis in response to different stressors. Upon lysosomal membrane permeabilization, cells activate several mechanisms for lysosomal membrane repair, including ESCRT proteins, phosphatidylinositol 4-phosphate (PI4P)-dependent lipid transfer from the...

Maja Radulovic, S. Pust, Athanasios Kournoutis et al. · 2 citations

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