Di-Hang Shi

Chlorogenic Acid Attenuates Liver Fibrosis in Mice via HIF-1α Inhibition and M2 Macrophage Polarization.

INTRODUCTION Liver fibrosis, a key pathological step preceding cirrhosis, is characterized by the abnormal accumulation of extracellular matrix (ECM) components, a process largely driven by hepatic stellate cell activation and persistent chronic inflammation. Chlorogenic acid (CGA), a natural polyphenolic compound, has...