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Author

Di Wu

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Open access Aug 2026

Orthogonal DNA barcoding enables subpopulation-resolved extracellular vesicle miRNA profiling

Extracellular vesicle–associated microRNAs (EV-miRNAs) hold promise for liquid biopsy, but their clinical utility is hindered by EV heterogeneity. Here, we report DEEPER, a DNA-encoded orthogonal recognition platform for selective barcoding of tumor-derived EV subpopulations and in situ miRNA profiling. DEEPER uses fou...

Ye Zhang, Yi-Tong Zhu, Yu Zhang et al. · 0 citations
Aug 2026

[Prediction and verification of therapeutic drugs for triple-negative breast cancer using a knowledge graph-based drug repurposing model].

The KGNN model can effectively predict drug-target interactions to facilitate drug repurposing and the design of multi-target drugs while reducing the screening space and experimental validation costs.

Di Wu, Zhan-Fa Xu, Yi Li et al. · 0 citations

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