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Author

Dian-Ke Yu

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Sep 2026

Targeting IGF2BP3-driven CSF1/CSF1R signaling disrupts the positive feedback loop between tumor cells and macrophages and inhibits HCC progression.

It is revealed that IGF2BP3 drives HCC malignancy by establishing a reciprocal interaction between tumor cells and macrophages via the CSF1/CSF1R signaling pathway, highlighting that therapeutic targeting of this axis may disrupt tumor-macrophage crosstalk and improve therapeutic efficacy.

Xiao-Ying Ji, Lin-Ran Zhang, Xiao-Xiao Zhu et al. · 0 citations

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