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Author

Dibbanti HariKrishnaReddy

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Open access Aug 2026

Neuroprotective effect of normal and modified mesenchymal stem cell‐derived exosomes by mitigating Alzheimer's‐related oxidative and inflammatory damage via Nrf2/HO‐1 in SH‐SY5Y cells

Abstract Exosome therapy is emerging as a promising neuroprotective strategy for Alzheimer's disease (AD). We evaluated and compared whether normal exosomes (NE) and modified exosomes (ME) derived from AD rat brain extract‐treated rat bone marrow mesenchymal stem cells possess the potential to protect SH‐SY5Y cells aga...

Rishika Dhapola, Prajjwal Sharma, Sneha Kumari et al. · 0 citations
Review Aug 2026

HMGB1 signalling in Alzheimer's disease: pathogenic roles and therapeutic prospects.

High mobility group box 1 (HMGB1) is a crucial modulator of neuroinflammation in AD, according to new research, and a viable treatment approach for reducing neuroinflammation and associated pathologies with AD is to target HMGB1-mediated signalling networks.

Prashant Tyagi, Sneha Kumari, Prajjwal Sharma et al. · 1 citation

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