The complex role curcumin plays in the fight against cancer is demonstrated and how crucial it is to get past pharmacokinetic obstacles in order to fully utilise its therapeutic potential is stressed.
K. Sannidhi, Navya, A. M. Ashesh et al.· Current Cancer Therapy Revie...· 0 citations
In this computational study, the thiazole-linked isoxazole compound C139 demonstrated probable antidiabetic activity against PPARγ, but these findings remain predictive and require further validation through comprehensive in vitro and in vivo studies.
Abhirami Pv, Gupta Dheeraj Rajesh, N. V. L. Sirisha Mulukuri et al.· Frontiers in Bioinformatics· 0 citations
The Alzheimer's Disease (AD) lacks effective disease-modifying therapy, even though amyloid-targeting immunotherapies have recently been applied clinically. N-methyl-D-Aspartate Receptors (NMDARs) play a central yet mechanistically complicated role in the pathophysiology of AD, where they are convergence points of amyl...
Md Sirajuddin Khan, A. M. Ashesh, Mithul V. Mammen et al.· Current Neuropharmacology· 0 citations
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