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Dina Dadabhoy

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Aug 2026

Hepatotoxicity of Avacopan: Real-World Incidence and Confirmed Cases of Severe Drug-Induced Liver Injury in a US National Rheumatology Registry.

INTRODUCTION Avacopan, an oral C5a receptor inhibitor, approved for ANCA-associated vasculitis (AAV) in 2021. Following FDA reports of 76 worldwide drug induced liver injury (DILI) cases (66 in Japan, 5 in the US), the agency requested market withdrawal, which the manufacturer declined. US risk has not been quantified...

Eric T. Roberts, Dina Dadabhoy, Ryan Antolini et al. · 0 citations

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