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Author

Dina Pereira

2 papers indexed here

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Open access Aug 2026

Importin-8 silencing reduces Ataxin-3 aggregation and alleviates Machado-Joseph disease/spinocerebellar ataxia type 3

Summary Machado-Joseph disease (MJD) is a polyglutamine neurodegenerative disorder characterized by the formation of neuronal intranuclear Ataxin-3 inclusions. The nucleocytoplasmic transport is known to be profoundly dysregulated from early stages of neurodegeneration, further aggravating its progressive nature. To un...

Inês Morgado Martins, A. Sowa, David Rufino-Ramos et al. · 0 citations
Review Open access Jul 2026

Cognitive dysfunction in Parkinson's disease: Hippocampal vulnerability and redox-driven mechanisms.

This review positions redox dysregulation – and NOX-dependent signaling in particular – as a unifying mechanism underlying cognitive decline in PD, and discusses emerging therapeutic strategies targeting redox pathways, highlighting NOX modulation as a promising approach to modify the course of Parkinson's disease-asso...

Ana Rita Curto, A. A. Silva, M. Fiadeiro et al. · 0 citations

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