This review covers current breakthroughs in sulfonamide derivative production, biological activity, resistance mechanisms, and therapeutics and nanotechnology, AI-assisted drug discovery, and multitarget therapy design which increase sulfonamide-based treatment selectivity and efficacy.
Dina Saleem, Hawazin Aziz Hamim, Sura S. Raoof· South Asian Research Journal...· 0 citations
Overall, this study identifies selected 4-oxoquinazoline hydroxamic acid derivatives as preliminary computational leads for further experimental validation as potential HDAC8-targeting compounds.
Dina Saleem, M. Mahdi, Ayad Mohammed Rasheed· Pharmacia· 0 citations
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