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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Dinesh S. Rao

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Open access Sep 2026

IGF2BP3 remodels RISC occupancy to control microRNA targeting in leukemia

Abstract IGF2BP3 is an oncofetal RNA-binding protein that promotes leukemogenesis, but the mechanisms by which it remodels post-transcriptional gene regulation remain incompletely understood. Because IGF2BP3 binds extensively within 3′ untranslated regions and has been implicated in microRNA (miRNA)-mediated regulation...

Lyna E. S. Kabbani, S. Kapoor, Gunjan Sharma et al. · 0 citations
Open access Jul 2026

Targeting RNA-Binding Oncofetal Protein IGF2BP3: Discovery of Potent and Selective Inhibitors

Beyond enabling the discovery of several new potent and selective small molecules, these studies have allowed us to elucidate key parameters for potency, selectivity, and metabolic stability that should aid future efforts in RBP drug discovery.

G. M. Scherer, Jacob P. Sorrentino, A. K. Jaiswal et al. · 0 citations

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