Sequence-Programmable Iron Oxide Nanoparticles Enable Dual-Phase T1-Weighted MRI of Ultrasmall Hepatocellular Carcinoma and Tumor Vascular Architecture.
Early-stage hepatocellular carcinoma diagnosis is hindered by the inability of conventional MRI to concurrently detect tiny tumors and delineate their microvascular networks. To address this, we engineered sequence-programmable iron oxide nanoparticles with precisely tuned magnetic properties that enable dual-phase T1-...