Sep 2026
The miR-6538 in extracellular vesicles derived from lycorine-pretreated mesenchymal stem cells enhances therapeutic efficacy in rheumatoid arthritis.
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) were engineered as a targeted platform for Lycorine (LYC), a natural isoquinoline alkaloid with anti-inflammatory and anti-neoplastic properties that exhibits therapeutic potential in inflammatory diseases but is limited by systemic toxicity in clinical app...
Wu-Yan Zheng, Xiong-Fei Xu, Chen-Xu Yang et al.
· Biomaterials · 0 citations