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Ding-Wang Hu

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Oct 2026

Paeonol alleviates oxidative stress and brain injury in hypoxic-ischemic encephalopathy by activating the PI3K/Akt/Nrf2 signaling pathway.

BACKGROUND Hypoxic-Ischemic Encephalopathy (HIE) is a severe neonatal neurological disorder, in which oxidative stress serves as a central mediator of brain injury. Paeonol (Pae), a phenolic compound with established anti-inflammatory and antioxidant properties, remains underexplored as a therapeutic strategy for HIE....

Ding-Wang Hu, Jiang-Han Li, Ling-Bin Ye et al. · 0 citations

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