ABSTRACT β‐Chiral phenethyl alcohols represent a privileged scaffold in bioactive molecules, chemical probes, and functional materials, serving as versatile synthons in organic synthesis. Herein, we report the first Ni/photoredox‐catalyzed stereoconvergent C(sp3)−C(sp2) cross‐electrophile coupling of racemic epoxides w...
Hongyan Lan, Sheng-Zhou Jin, Zhao-Dong Xu et al.· Advancement of science· 0 citations
Axially chiral N‐heterobiaryls are important structural motifs in asymmetric catalysis, medicinal chemistry, and chiral functional materials. Their enantioselective synthesis has traditionally relied on noble‐metal catalysis or resolution‐based strategies, which often suffer from high cost, limited modularity, and rest...
Bao-Juan Wang, Xin Ren, Chenguang Ding et al.· Annalen der Pharmacie· 0 citations
Mechanochemistry has evolved beyond its traditional role as a sustainable alternative to solution‐phase synthesis and is now recognized as a distinctive catalytic platform in which mechanical force can regulate bond activation, redox processes, catalyst speciation, and reaction selectivity. Foundational progress in thi...
